Patient's question:
Female, 28 years old. 13 weeks pregnant. The female is O-type blood, and the male is AB-type blood. Currently, there is a detection of hemolysis, and the values are slightly high. How might this affect the child?Doctor's answer:
ABO blood type incompatibility is more common when the mother is type O, the father is type A, B, or AB, and the fetus is type A or B. IgG antibody titer should be measured periodically: every two weeks from weeks 28 to 32 of pregnancy, and weekly from week 32 onwards. In cases of ABO blood type incompatibility, if the titer of autoantibody anti-A (or anti-B) exceeds 1:128, hidden fetal hemolysis is suspected, and if the titer exceeds 1:512, fetal hemolysis is highly suspected.