Patient's question:
What is the relationship between epilepsy and immunology?Doctor's answer:
I. The Concept of Immunity: Immunity is an important defensive function of the body that protects organisms by excluding foreign substances, maintaining purity, and ensuring stability, including immune responses, immune surveillance, and immune stability. If a person's immune function is low, they are more prone to catching colds and infections. If the immune function is too strong, it can lead to allergic reactions or autoimmune diseases.II. The Relationship Between Immunity and Epilepsy: Through our research, we believe that some epilepsy patients have abnormal immune functions, mainly including cellular immunity and humoral immunity. The use of immunoglobulins to treat refractory epilepsy in children has shown good effects, proving that epilepsy is related to immune abnormalities.
1. Autoimmune damage can cause epilepsy recurrence.
2. Cryptogenic epilepsy has a consistent relationship with immune genetics.
3. Immune abnormalities present before antiepileptic drug treatment in some patients are one of the factors or causes of epilepsy recurrence.
4. Epilepsy children with a history of febrile seizures often have IgA deficiency.
5. Immune damage can cause brain epileptic discharges or clinical recurrence. Therefore, the treatment of epilepsy should fully consider immune function abnormalities, which is often overlooked by doctors. Special attention should be given to children who frequently catch colds. Hospitals with the necessary conditions should carry out relevant tests.
III. Immune Therapy:
1. Method: Oral immunoglobulins, with a two-month course as one cycle. A total of two to three cycles.
2. Indications: Children with epilepsy who have a history of febrile seizures or frequently catch colds; children with epilepsy who have weak constitutions; refractory epilepsy in children.