Does cholestasis cause fetal malformations?

Patient's question:

I am very scared when this happens. I often have lower abdominal pain and don't know how to solve it, so I came here to consult. Can bile acid cause fetal malformations?

Doctor's answer:

The impact on the fetus and mother should be determined based on the specific disease. If it is idiopathic intrahepatic cholestasis of pregnancy (IICP), it is generally controllable with timely and appropriate treatment, and symptoms typically improve after delivery. However, if high levels of bilirubin remain elevated for a long time, it may affect the fetal central nervous system or the mother, leading to conditions such as kernicterus. Generally, doctors recommend that women with risk signs of prenatal examinations maintain personal hygiene and avoid sexual activity. Additionally, patients should create an environment conducive to emotional stability and stress relief. Wishing the patient a healthy delivery.

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