How to solve positive antisperm antibodies

Patient's question:

Positive antisperm antibodies, weak sperm, enhance sperm nutrition, three-in-one, what does it mean? Do you have any good prescriptions?

Doctor's answer:

Hello; Antisperm antibodies are a complex pathological product, affecting both men and women, with their exact causes or etiology not yet fully understood. The sperm and seminal plasma of men are specific antigens for women. Upon contact with the bloodstream, they can trigger immune responses in both men and women, leading to the production of corresponding antibodies that hinder sperm from fertilizing eggs, resulting in infertility. The aforementioned conditions fall under the category of immunological infertility. When sperm antigens come into contact with the immune system, the body produces antisperm antibodies, causing sperm to aggregate, become immobilized, lose their normal vitality, and struggle to fertilize eggs. In cases of asthenozoospermia, sperm lack the strength to move forward, making it difficult for them to penetrate the cervical canal, uterine cavity, and reach the fallopian tubes to fertilize eggs, thereby reducing fertility. Common causes or etiologies of asthenozoospermia include: 1. Incomplete maturation or damage to the spermatogenic epithelium in the testes, leading to poor sperm quality and weak motility; 2. Low seminal fluid volume; 3. Seminal plasma abnormalities, such as inflammation in the epididymis, seminal vesicles, or prostate, which can negatively affect sperm activity and survival due to changes in pH, oxygen supply, nutrition, and metabolism. If antisperm antibodies are present, they can cause sperm to aggregate, rendering them inactive. Our hospital is a modern specialized facility established in full compliance with the World Health Organization's standards for diagnosing and treating human infertility. For immunological infertility, we employ isolation therapy and immunosuppressive therapy. We recommend that you visit our hospital for early treatment and do not miss the best age for conception. If you have any questions, please feel free to contact us! Wishing you good health!

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