Patient's question:
The risk rate of Down syndrome during pregnancy, as determined by the detailed examination, is Trisomy 21 1/669. The AFP test result is 32.4 U/ML; the MOM value is 0.85. The HCG test result is 24.3 ng/ML; the MOM value is 1.43. The risk rate of Trisomy 18 is 1/59,826. I had blood drawn at 16 weeks and 2 days of pregnancy. The report indicates a critical risk for Trisomy 21, suggesting close monitoring. The report notes a low risk or negative result, but it cannot completely rule out the possibility of fetal abnormalities or other abnormalities. Is this result normal? Is it still necessary to undergo amniocentesis? In terms of help: Should I still have a painless DNA test or amniocentesis?Doctor's answer:
Based on the described situation, it is a case where the critical risk of recurrence of Trisomy 21 syndrome has reappeared. The recurrence of this condition indicates that the likelihood of the fetus having Down syndrome again is approximately 1 in 669. Generally, after this situation reoccurs, it is still recommended to promptly undergo non-invasive DNA testing or amniocentesis for re-examination. As long as the re-examination result is low risk, you can focus on early pregnancy. If the risk remains high, it is not advisable to focus on early pregnancy.