Patient's question:
Recently I've been quite irritable and under significant mental stress, making it easy for depressive relapse to occur again. I'm experiencing symptoms of menopause again, such as hot flashes, excessive thirst, sleep disturbances, and low mood. However, after a thorough medical examination, it was found that I have premature ovarian failure. What kind of assistance do I need: What are the symptoms of premature ovarian failure?Doctor's answer:
Premature ovarian failure refers to a condition in women who have previously experienced natural menstrual cycles but exhibit persistent ovarian atrophy and amenorrhea before the age of 35. Clinically, it is characterized by the regression of secondary sexual characteristics, along with menopausal symptoms such as facial flushing, irritability, and restlessness. Affected individuals are prone to frequent colds, with a significantly decreased level of follicle-stimulating hormone (FSH) reaching 40 units or higher, equivalent to postmenopausal levels, and a markedly reduced level of estradiol. Gynecological examinations reveal significant expansion of the internal reproductive organs, with thin and congested vaginal mucosa. Laparoscopic ovarian biopsy confirms atrophy, with microscopic examination showing that the ovarian cortex is composed entirely of fibrous tissue, devoid of primordial follicles or any other stages of follicles.