Patient's question:
Irregular menstruation for over two months, after a thorough examination, the doctor believes there may be polycystic ovary syndrome. After taking progesterone for one day, the period started on the third day. The doctor suspects insulin resistance. During the menstrual period, fasting blood glucose was 4.6 mmol/L, fasting insulin was 3.51 uU/ml, insulin at one hour was 58.27, and at two hours was 43.07. Blood glucose levels at one hour and two hours were not measured. Is this a relatively severe case of insulin resistance? I feel that my insulin level after drinking glucose is not particularly high in absolute terms, but relatively high compared to the fasting value. Should I take metformin?Doctor's answer:
Your insulin multiple exceeds 16 times, but the absolute value is not high. From the trend, the insulin level at 3 hours should be able to drop to the normal reference value, so it is not severe insulin resistance, but at most slightly elevated insulin resistance. It is necessary to diagnose whether it is polycystic ovary syndrome (PCOS). The following should be checked: no menopause or minimal menopause, menstrual irregularities (signs of high androgens or urinary test values, or bilateral small follicles less than 12 in B (many ultrasound doctors are accustomed to using 10 as the threshold when writing B reports). If the above conditions are met, it can be diagnosed as PCOS.