Molecular medicine of apoptosis

Author: Hu Ye
Publisher:
Publish Date: 2002-02-01
Features: This book is a comprehensive and systematic monograph on apoptosis. It is divided into four parts. The first part focuses on elaborating the fundamental theories of apoptosis, including basic concepts, biological characteristics, regulatory genes and factors, signal transduction pathways, enzymatic basis, and their relationships with integrins, reactive oxygen species, cytokines, and immunology. It also explores the inducers of apoptosis and the mechanisms of clearance of apoptotic cells. The second part emphasizes the interrelationships between apoptosis and various systemic diseases, such as those affecting the cerebrovascular, cardiovascular, liver, kidneys, skin, nervous system, reproductive system, and digestive system, as well as trauma, hematological diseases, AIDS, tumors, autoimmune diseases, and infectious diseases in terms of their mechanisms of occurrence and development. The third part introduces the clinical applications of apoptosis, primarily focusing on its use in disease diagnosis and treatment, including drug development, bioproduction, radiotherapy and chemotherapy for tumors, and exploring tumor gene therapy from the perspective of promoting apoptosis. The fourth part provides detailed descriptions of commonly used techniques in apoptosis research, including experimental principles, operational methods, reagent preparation, and operational precautions, making it particularly practical. This book is suitable for graduate students and researchers in various disciplines of life sciences, especially medical researchers and clinical doctors for reference.