Does blood type have anything to do with recurrent miscarriage?

Patient's question:

Returned to me, when I was 2 months pregnant and had an ultrasound, it was found that the baby had no heartbeat. At that time, my husband and I were very painful. This is the child we have been looking forward to, and it is also my first child. How could this situation reappear? Is there a relationship between blood type and fetal arrest?

Doctor's answer:

If the blood types of the couple do not match, the fetus may inherit the blood type antigen lacking from the mother through paternal generation. Once these red blood cells enter the mother's body, the mother's body will produce antibodies. These antibodies can cross the placenta into the fetus, leading to the destruction of the baby's red blood cells. Embryonic arrest is just one of the severe consequences. If the couple discovers the blood type mismatch before pregnancy, they should enhance monitoring during the pregnancy.
After three months of pregnancy, women can undergo a blood test to check the titer of serum antibodies. If the wife is type O blood and the husband is type A, B, or AB blood, there may be an ABO blood type incompatibility between the mother and fetus. Other reasons for embryonic arrest include the relationship between autoimmune antibodies and embryonic arrest.

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