Is a trisomy risk number of 1/373 from the Down syndrome screening important?

Patient's question:

Doctor, the second child policy is now open. My daughter is already in junior high school. Because I really want children, getting pregnant at this age is also very very hard. I had a thorough check-up at the hospital and they said my risk coefficient for trisomy 21 in the triple screen test is 1/373. Is it urgent? What should I do?

Doctor's answer:

Your careful examination result is at the critical value, it hasn't reached the high-risk level, which also proves that there is a possibility of recurrence of Down syndrome. If you are not at ease, you can have an amniocentesis or chorionic villus sampling for a detailed check, but this is an invasive examination. Alternatively, you can have a non-invasive DNA test to clarify the situation, but the cost will be much higher. If you are planning to conceive, it is recommended to have a comprehensive examination.

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