What are the two major symptoms of acute appendicitis?

Patient's question:

What are the two major symptoms of acute appendicitis. I've been experiencing it since two days ago, suddenly feeling a sharp pain in the right lower abdomen, specifically in a vertical line, like being pricked by a needle. Moreover, whether using a hot water bag or cold compress, or even self-massage, it doesn't relieve the pain at all.

Doctor's answer:

If manual massage cannot alleviate acute gynecological inflammation, this is quite normal. Acute adnexal inflammation is itself caused by bacterial pathogens. Using a hot water bag for cold compress is only a temporary and mild relief, and massage has almost no absolute effect. What is needed is the coordination of antibiotic treatment for the primary condition to completely eliminate the pathogens, which can then effectively alleviate the symptoms. Medications such as quinolone-class drugs combined with nitrofurantoin are recommended.

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