Why does chemotherapy after liver resection cause menstrual disorders?

Patient's question:

A year ago, I developed a malignant liver tumor. The doctor recommended surgery to remove it to prevent it from spreading. One month after the liver resection surgery, I underwent chemotherapy, and my menstrual cycle started to become irregular. It never arrived on time, and when it did, it came with severe abdominal pain that was far worse than usual. The menstrual flow was heavy and thick, consisting of clots of blood. What could be the reason for the menstrual irregularity after one month of chemotherapy following liver resection surgery?

Doctor's answer:

Irregular menstruation can be affected by mental and emotional stress, medication, irregular sleep patterns, diet, endocrine disorders, diseases, and other factors. If you have undergone liver surgery and chemotherapy, it is highly likely that the irregular menstruation is caused by the disease and medication. It is recommended to undergo a thorough examination, including an ultrasound, six sexual hormones tests, and a routine vaginal discharge test, to clarify the diagnosis. After diagnosis, symptomatic treatment should be administered. During this period, attention should be paid to diet, enhancing external genital hygiene, and maintaining a stable emotional state.

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