What does a high risk result on the Down syndrome screening mean?

Patient's question:

During the prenatal check-up last week, I was found to have a high risk of Down syndrome screening. The doctor said it might be necessary to have an amniocentesis, but it is said that this procedure involves an incision. I would like to ask, what does a high risk of Down syndrome screening mean? Is it necessary to have an amniocentesis?

Doctor's answer:

Down syndrome screening high-risk indicates a higher risk of the fetus having Down syndrome. After a high-risk result from Down syndrome screening during prenatal care, the pregnant woman does not necessarily need to undergo amniocentesis. Non-invasive DNA testing is also an option. Non-invasive DNA testing has an accuracy rate of 99.99%; amniocentesis has an accuracy rate of 100%. Decide based on your personal situation. If you are concerned about psychological trauma, you can choose non-invasive DNA testing; if you want a 100% accuracy rate, you should choose amniocentesis.

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