What is the meaning of an abnormal Triple Screen (UE3) in Down syndrome screening?

Patient's question:

This is the first time I'm going to be a mom, and some things are a bit tight. Today, I went for a Down syndrome screening, and it said ue3mom abnormal. I'm a bit worried, but the doctor didn't say anything, just said to come back for a follow-up. I'm very anxious. What does Down syndrome screening ue3mom abnormal mean?

Doctor's answer:

To refer but do not over worry. The triple screen test is a prenatal screening test for Down syndrome. If the results of the triple screen test are abnormal, the risk of the fetus having Down syndrome should be further evaluated through diagnostic tests such as amniocentesis or chorionic villus sampling. Sometimes, the first screening result may be abnormal, but the second test may be normal. Pay special attention to the development of the neural tube. Pay attention to taking folic acid and vitamins.

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