What is the critical risk value for Down syndrome screening generally?

Patient's question:

I am pregnant and have a few months to do a detailed screening for Down syndrome. The report shows a critical risk. I would like to ask what is the general critical risk value for Down syndrome screening?

Doctor's answer:

The critical risk value for Down syndrome screening is approximately 1/700. When the urine screening value is greater than 1/270, it is considered high-risk; the normal value is around 1/700. The international standard is 1/270. Additionally, the Down syndrome screening value is a corrected value. Down syndrome screening provides a risk assessment, with a critical value of 1/27. Values above this are high-risk, and those below are low-risk.
Down syndrome screening is typically performed between weeks 14 and 19 of pregnancy. It is related to the pregnant woman's age and the fetal growth and development. It serves as a preliminary examination to check for any abnormalities in the chromosomes.

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