How many weeks into pregnancy should you have the Down syndrome screening?

Patient's question:

I just checked that many experienced friends need to do a lot of careful checks after getting pregnant, and the prices are also very high. I wonder how long you should do the Down syndrome screening after getting pregnant?

Doctor's answer:

The best time to undergo screening is between the 15th and 20th weeks of pregnancy. After a blood test, the results can usually be available within one week. If the screening results indicate a high risk, there is no need to panic because further tests such as amniocentesis and fetal chromosome analysis are required to confirm the diagnosis.
Down syndrome screening is a test that involves extracting a pregnant woman's blood to examine the levels of alpha-fetoprotein and human chorionic gonadotropin in the maternal serum. By combining this information with the pregnant woman's due date, age, weight, and gestational age at the time of blood collection, the test estimates the risk of giving birth to a child with Down syndrome.

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