Patient's question:
I have lupus nephritis, but I accidentally got pregnant with twins this year, so I want to ask if there is a higher risk of miscarriage with medication abortion for lupus nephritis?Doctor's answer:
Lupus nephritis patients, due to long-term use of hormones and immunosuppressants, have a relatively high risk of intrauterine transmission. It is recommended that small patients undergo surgery during pregnancy, as the incidence of miscarriage, stillbirth, and premature birth is increased. Postpartum, the condition continues to worsen. If delivery occurs, postpartum inflammation may develop, with a perinatal mortality rate of 37%. Some reports suggest that lupus nephritis during pregnancy can lead to remission, with no significant increase in premature birth or stillbirth rates. Most scholars advocate increasing the dose of hormone therapy during pregnancy and postpartum. In past clinical diagnoses, systemic lupus was often terminated in early pregnancy. However, it is now believed that despite the high perinatal mortality rate, treatment should still be based on specific clinical conditions.