Patient's question:
Hello, what are the harms of immunological infertility? What are the harms of immunological infertility?Doctor's answer:
Hello, the harms of immunological infertility are as follows:1. Blocking sperm from penetrating cervical mucus, anti-sperm antibodies can cause sperm to clump together, hindering sperm movement. Sperm immobilizing antibodies have cytotoxic effects, leading to sperm death or affecting sperm motility. Additionally, they may also impact sperm metabolism and the function of sperm condensing proteins.
2. Affecting the movement of sperm enzymes, inhibiting the concentration of the zona pellucida and the corona radiata, including:
① Acrosin: Enhances sperm penetration through the zona pellucida and promotes fertilization;
② Hyaluronidase: Enables the corona radiata (egg) to concentrate, all of which contribute to immunological infertility.