I want to know what are the causes of premature ovarian failure

Patient's question:

My mom is 40 years old this year, but she has already gone through menopause. Then, after a thorough examination at the hospital, it was found that it was due to premature ovarian failure. What could cause premature ovarian failure? Because I'm upset, I will never want to experience early menopause like my mom. What should I do? Please help me understand, thank you.

Doctor's answer:

Premature Ovarian Failure: 4 Causes
1. Autoimmune Factors. Accounting for approximately 20%, ovarian antibodies can be detected in the blood. These patients often have other autoimmune diseases such as lupus, rheumatoid arthritis, or a congenital deficiency of an enzyme.
2. Cytogenetic Factors. Congenital scarcity of germ cells, accelerated atresia of follicles, and abnormal X chromosomes. 10% of patients have a family history.
3. Physical Factors.