Patient's question:
Please check carefully, it is endometrial hyperplasia. I don't know how to treat it well? Is there any way to solve it? It has been troubling me for a long time, and my heart is not comfortable. I am looking for a solution.Doctor's answer:
Drug treatment.(1) Ovulation-inducing drugs: Ovulation-inducing drugs include clomiphene and human chorionic gonadotropin (HCG). They are generally used for patients with mild atypical hyperplasia of the endometrium. The dosage of clomiphene is 50–100 mg, once daily, taken orally on days 5–9 of the cycle. The medication period may be extended by 2–3 days if necessary.
(2) Progestin drugs: Progestin drugs can inhibit estrogen-induced endometrial hyperplasia. Their mechanism of action includes:
① By inhibiting the secretion of hypothalamic and pituitary gonadotropins, they raise serum E2 levels to the level of the early follicular phase.
② Reducing the estrogen nuclear receptor levels in the endometrium.
③ Inhibiting DNA synthesis in the endometrium.
④ Enhancing the activity of estrone dehydrogenase and isocitrate dehydrogenase.