Patient's question:
I've been married for several years, and so far, we haven't had any children. I'm very anxious about it and don't know if it's my problem. I've asked my husband to get checked, but he refuses. I'm very worried that my condition might worsen. Please advise on how to alleviate immune infertility.Doctor's answer:
The sperm and seminal fluid of males are considered specific antigens for females. Upon contact with blood, they can trigger autoimmune reactions in both men and women, leading to the production of additional antibodies that hinder the combination of sperm and eggs, resulting in infertility. The goal of alleviating immunological infertility is to reduce the titer of anti-sperm antibodies in the body, even eliminating them, so that sperm and eggs can combine normally, allowing for childbirth.The primary method for alleviating immunological infertility is isolation therapy: this involves using condoms to prevent and reduce contact between the female reproductive tract and sperm and their antigens, thereby preventing the formation of new antibodies. Generally, this isolation is maintained for 6-12 months, during which the titer of anti-sperm antibodies in serum and cervical mucus is monitored. Once it returns to normal, childbirth may be possible.