How to treat immunological infertility?

Patient's question:

How to treat immunological infertility I've been married for several years now and still haven't had any children. I'm very anxious myself, not knowing if it's my problem. I asked my husband to get checked, but he refuses. I'm afraid my condition will worsen. What should I do?

Doctor's answer:

Immunological infertility refers to a condition where the patient has normal menopause and reproductive tract function, no evidence of sepsis in direct relatives, and normal semen analysis results, but there is evidence of anti-pregnancy autoimmune response. It is caused by autoimmune or allogeneic autoimmune response to antigens in the reproductive system. The tests for autoimmune factors believe that there are mainly two types: anti-sperm and anti-ovum zona pellucida autoimmune infertility. Due to the limited tests for the latter so far, clinical diagnosis of immunological infertility mostly refers to anti-sperm autoimmune infertility. Modern medicine believes that the immune system is a highly complex system, regulated by the nervous and endocrine systems, and in turn, it also adjusts the nervous and endocrine systems, forming a neuroendocrine-immune regulatory network.

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