Patient's question:
Where can I get help and how to treat immunological infertility? Hello, doctor, my friend has been diagnosed with immunological infertility, and she is very worried about her future fertility. Hello, where should I go for treatment? Where can I get help and how to treat immunological infertility?Doctor's answer:
The hazards of immunological infertility include the following points:1. Blocking sperm from penetrating cervical mucus, anti-sperm antibodies can cause sperm to clump together, hindering sperm movement. Additionally, anti-sperm antibodies exhibit cytotoxic reactions, leading to sperm death or affecting sperm mobility. Furthermore, they may also have some impact on sperm metabolism and the function of sperm condensation proteins.
Affecting the movement of sperm enzymes, inhibiting the aggregation of the zona pellucida and the corona radiata, including:
① Acrosin: Can enhance sperm penetration through the zona pellucida and promote fertilization;
② Hyaluronidase: Can cause the cumulus oophorus (corona radiata) to aggregate.
Anti-sperm antibodies primarily inhibit the activity of hyaluronidase, affecting sperm aggregation.
Affecting embryonic development and growth.