Patient's question:
What is the most basic cause of immunological infertility? I have been married for several years, but I still don't have any children. I am very anxious myself, not knowing if it's my problem. I asked my husband to get checked, but he refuses. I'm afraid my condition will worsen. What is going on?Doctor's answer:
1. Autoimmune of the same species: Refers to the sperm and seminal plasma of the male acting as antigens in the female body, producing antibodies to cause sperm agglutination or loss of motility. Under normal circumstances, women do not produce autoimmune reactions, but about 15%-18% of infertile women have anti-sperm antibodies.2. Local autoimmune: Refers to some infertile women's cervical mucosa and endometrium containing lymphoid cells that produce immunoglobulin G and A, and the immunoglobulin G, A, and M contained in cervical mucus that are anti-sperm. Therefore, the cervix and female reproductive tract have a local autoimmune effect on sperm. Immunological infertility is a gynecological disease that is prone to occur. During treatment, women need to pay attention to their own care.