How to treat immunological infertility

Patient's question:

I've been married for several years, but so far, I haven't had any children. I'm very anxious about it and don't know if it's my problem. I've asked my husband to get checked, but he refuses. I'm afraid my condition will worsen. What should I do about immune infertility? How should it be treated?

Doctor's answer:

Immune infertility generally has no obvious symptoms. If a couple has been married without using contraception and has not been able to conceive after normal sexual intercourse for more than 2 years, and both partners have no obvious reproductive system disorders, then it is necessary to consider the possibility of immune infertility. Additionally, men may develop antisperm antibodies due to damage to the blood-testis barrier, leading to an autoimmune response. Therefore, men who have had conditions such as vas deferens injury or epididymitis should be more vigilant. Treatment should be determined based on the underlying cause, and assisted reproductive technologies such as artificial insemination may be used when necessary. Immune infertility patients can still conceive. Currently, there are many methods to treat immune infertility, but it is necessary to test for autoimmune reactions in both partners before treatment.

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