Patient's question:
Diagnosed with infertility for many years, I have seen many doctors and visited many hospitals, but I have never been able to conceive successfully. I am about to give up. Please ask: What is the best treatment for immunological infertility?Doctor's answer:
Immune infertility refers to infertility caused by immune factors. Immune infertility accounts for approximately 10-30% of infertility cases, including various types such as anti-sperm antibodies, anti-endometrial antibodies, anti-ovum antibodies, and other immune-related infertility. Clinically, the most common form is immune infertility caused by the production of anti-sperm antibodies. Due to reproductive tract inflammation in women, local secretion increases, allowing autoimmune cells to enter the reproductive tract. Simultaneously, changes in the reproductive tract mucosa reduce the processing of sperm antigens. Additionally, bacterial, viral, and other infectious agents may act as natural adjuvants, reducing the body's autoimmune response to sperm antigens. As a result, anti-sperm antibodies reappear in the local reproductive tract and bloodstream, affecting sperm vitality and hindering fertilization, leading to infertility.