What are the surgical treatment methods for immunological infertility?

Patient's question:

Married for many years, I have been actively trying to conceive with my husband, but there has been no good news so far. I am very anxious. Could you please tell me about the surgical treatment methods for immunological infertility?

Doctor's answer:

Hello, the more common treatments for immunological infertility include:
1. Preventing antigen contact. Using condoms during each sexual encounter can prevent further stimulation of the female by sperm antigens. Once the female's sperm antibody levels decrease, encourage the patient to have unprotected intercourse during the ovulation period or undergo artificial insemination.
2. Immunosuppressive methods. Corticosteroid drugs have anti-inflammatory effects and can affect macrophage toxicity, making them suitable for treating immunological infertility.
3. In vitro fertilization. Sperm and eggs are cultured in vitro to form a zygote, which is then implanted into the uterine cavity 35 days after fertilization. Thus, sperm does not need to come into contact with the female reproductive tract, which contains sperm antibodies, before fertilization. After fertilization, due to the protective function of the zygote's semi-transparent membrane, sperm antibodies cannot remotely attack the zygote. Subsequently, the zygote implants.

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