Patient's question:
Married for many years, I have been actively trying to conceive with my husband, but there has been no good news so far. I am very anxious. How should immune infertility be treated?Doctor's answer:
1. Barrier therapy: For women with sperm alloimmunization infertility, using condoms for 3 to 6 months can prevent further stimulation of sperm antigens by the female. After the antibody titer decreases, sexual intercourse during the ovulation period is recommended, which may lead to pregnancy.2. Gamete intrafallopian transfer (GIFT): Clinical studies have found that GIFT for autoimmune infertility males and their immediate family members results in pregnancy for 43% of couples. Therefore, it is believed to be a highly effective and safe treatment for immunological infertility.
3. Immunosuppressive therapy: Corticosteroids can be used to treat immunological infertility.
4. In vitro fertilization and embryo transfer (IVF): If a woman has persistently high-titer anti-sperm antibodies, it is a contraindication for IVF.