What are the therapies for immunological infertility?

Patient's question:

I met my husband when I was in university, and we never took any contraceptive measures while dating. However, I have never been pregnant. Now that we are preparing to get married, my family elders keep urging me, which is really annoying. Please ask: What are the treatments available for immunological infertility?

Doctor's answer:

1. Immunosuppressive therapy: Through the stimulation of adrenal cortical hormone drugs, immune infertility can be treated. For example, two weeks before menopause, prednisone 5mg can be taken three times a day. It also includes the local use of hydrocortisone for women with infertility caused by anti-sperm antibodies in cervical mucus.
2. Artificial insemination can be used: Once anti-sperm antibodies are present in cervical mucus, it can affect delivery. In this case, the husband's sperm can be fertilized in vitro to produce high-quality sperm, which can then be used for intrauterine insemination.
3. Barrier therapy: This primarily refers to women with sperm homologous immune infertility. Using condoms for several months can prevent sperm antigen stimulation of the female. After the antibodies disappear, the ovulation period can be determined for potential delivery.

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