Patient's question:
I haven't been able to conceive for about a year. When I went to the hospital for a check-up, I found out that I have immune infertility. How can immune infertility be treated effectively?Doctor's answer:
Hello, immunological infertility refers to infertility caused by immunological factors. Immunological infertility accounts for 10-30% of infertility cases, including various types such as anti-sperm antibodies, anti-endometrial antibodies, anti-ovum antibodies, and others. In clinical diagnosis, the most common form is immunological infertility caused by the production of anti-sperm antibodies. Due to inflammation in the female reproductive tract, local secretion increases, allowing autoimmune cells to enter the reproductive tract. Simultaneously, changes in the permeability of the reproductive tract mucosa enhance the processing of sperm antigens. Additionally, bacterial and viral infectious agents may act as natural adjuvants, increasing the body's autoimmune response to sperm antigens. As a result, anti-sperm antibodies reappear locally in the reproductive tract and in the blood, interfering with sperm vitality and hindering fertilization, leading to infertility.