Patient's question:
A while ago, I went to the hospital for a pre-pregnancy check-up. The doctor said I had immunological infertility. How did I get sick? I don't want to lose the right to be a mother. How should patients with immunological infertility avoid injuries through exercise?Doctor's answer:
The hazards of immunological infertility include the following points:1. Blocking sperm from penetrating cervical mucus, anti-sperm antibodies can cause sperm to clump together, hindering sperm motility. Sperm immobilizing antibodies exhibit cytotoxic reactions, leading to sperm death or interference with sperm movement. Additionally, they may disrupt sperm metabolism and the function of sperm condensin proteins.
2. Interfering with the movement of sperm enzymes, inhibiting the aggregation function of the zona pellucida and the corona radiata, including:
① Acrosin: Enhances sperm penetration through the zona pellucida and promotes fertilization;
② Hyaluronidase: Facilitates the aggregation of the corona radiata (egg coat). Sperm antibodies primarily inhibit the activity of hyaluronidase, thereby affecting sperm aggregation.