Patient's question:
I am thirty years old this year. Two years ago, I had a miscarriage, and then I haven't been able to get pregnant. I want to go to the hospital for a check-up. What are the good methods to treat immunological infertility?Doctor's answer:
About 10% to 20% of infertility cases are classified as immunological infertility. The main treatment methods include:(1) Barrier therapy: Women with sperm alloimmunological infertility who use condoms for 3 to 6 months can prevent further stimulation of sperm antigens by the female. After the antibody titer decreases, timed intercourse during the ovulation period can be attempted, with the hope of achieving delivery.
(2) Immunosuppressive therapy: Corticosteroid drugs can be used to treat immunological infertility. For example, prednisone 5mg three times daily is administered two weeks before menopause. There are also reports of local vaginal application of hydrocortisone to treat infertile women with anti-sperm antibodies in cervical mucus. The reported pregnancy rates range from 20% to 45%.
(3) Intrauterine artificial insemination: When sperm antibodies in cervical mucus affect delivery, the husband's semen can be processed outside the body.