Patient's question:
I am 30 years old this year. Two years ago, I had a miscarriage, and then I haven't been able to get pregnant. I want to go to the hospital for a check-up. How can I treat immune infertility to get better?Doctor's answer:
Immune infertility refers to infertility caused by immune factors. Immune infertility accounts for approximately 10-30% of infertility cases, including various types such as antisperm antibodies, anti-endometrial antibodies, anti-oocyte antibodies, and other immune-related infertility. Clinically, the most common form of immune infertility is caused by the production of antisperm antibodies. Due to reproductive tract inflammation in women, local secretion increases, allowing autoimmune-related cells to enter the reproductive tract. Simultaneously, changes in the reproductive tract mucosa enhance the processing of sperm antigens. Additionally, bacterial and viral infectious agents may act as natural adjuvants, increasing the body's autoimmune response to sperm antigens. As a result, antisperm antibodies reappear in the local reproductive tract and bloodstream, interfering with sperm vitality and hindering fertilization, leading to infertility.