How to treat immune infertility

Patient's question:

The first child I had three years ago was quite normal. But now, I'm trying for a second child, and it's been a long time with no success. I suspect it might be my problem. Please ask: How should one treat immunological infertility?

Doctor's answer:

Immune infertility refers to a condition where the patient has normal menopause and reproductive tract function, no signs of sepsis are detected, and the semen analysis of direct relatives falls within the normal range, but there is evidence of anti-fertilization autoimmune. It is caused by autoimmune or allogeneic autoimmune reactions to reproductive system antigens. In recent years, experiments on autoimmune factors have shown that there are mainly two types of immune infertility: anti-sperm and anti-ovum zona pellucida immunity. Due to the limited research on the latter so far, clinical diagnosis of immune infertility mostly refers to anti-sperm immune infertility. The causes of immune infertility require patients to seek medical treatment promptly to identify the specific reasons for immune infertility, so that targeted treatment can be administered to help women become pregnant.

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