Patient's question:
For a long time, I haven't been able to conceive. When I went to the hospital for a check-up, they said it was my problem that I haven't been able to have a child yet. I'm really very distressed. Could you please ask: What are the preventive measures for immunological infertility?Doctor's answer:
Hello, the harms of immunological infertility are as follows:1. Blocking sperm from penetrating cervical mucus, anti-sperm antibodies can cause sperm to clump together, hindering sperm movement. Sperm agglutinating antibodies exhibit cytotoxic reactions, leading to sperm death or interference with sperm movement. Additionally, they may disrupt sperm metabolism and the function of sperm condensing proteins.
2. Interfering with the movement of sperm enzymes, inhibiting the concentration of the zona pellucida and the corona radiata, including:
① Acrosin: Enhances sperm penetration through the zona pellucida and promotes fertilization;
② Hyaluronidase: Enables the corona radiata (egg coat) to concentrate. Sperm antibodies primarily inhibit the activity of hyaluronidase, affecting sperm concentration.
3. Interfering with embryonic growth and development.