Patient's question:
Female, 29 years old, currently 4 months pregnant. She went to the hospital for a non-invasive DNA test. She is full of anticipation for the new life in her belly. What are the differences between first-generation non-invasive DNA and second-generation?Doctor's answer:
The first-generation non-invasive DNA primarily tests for diseases related to fetal chromosome 21, chromosome 18, and chromosome 13, issuing reports for these three chromosomes. It cannot detect microdeletions, microduplications, partial monosomies, and trisomies.The second-generation non-invasive DNA can test for 10 chromosomal gene diseases, serving as an advanced product based on the first-generation non-invasive prenatal testing. It enhances sequencing depth and has successfully achieved a leap in the scope of examination, ranging from chromosomal aneuploidy to non-invasive chromosomal microdeletion and microduplication syndromes.