Why can't people with panda blood type have a second child?

Patient's question:

I am 32 years old, I have a blood type. When I gave birth to my first child, the doctor said there would be risks. My blood type is not good, but the birth process was relatively smooth in the end. Now I want to have a second child, but the doctor said it is better not to. Why can't people with a blood type have a second child?

Doctor's answer:

Panda blood, also known as RH-negative blood, is a relatively rare blood type. If a woman with RH-negative blood has not received RH-positive blood transfusions, she can become pregnant with her first child. However, she cannot have a second child because RH hemolysis can be much more severe than ABO hemolysis. If she becomes pregnant with a second child, it may lead to very serious hemolytic conditions, so for the safety of the pregnant woman, she cannot become pregnant with a second child.

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