What are the early symptoms of vulvar leukoplakia?

Patient's question:

I am a 66-year-old woman who suddenly felt unwell. After a check-up, I was diagnosed with this disease. Please ask: What are the early symptoms of vulvar leukoplakia?

Doctor's answer:

The clinical manifestations of vulvar leukoplakia include vulvar itching, sometimes accompanied by a burning or painful sensation. The affected skin appears rough and thickened like psoriasis, with scratches and occasional recurrent fissures. Local hypopigmentation is observed, with the labia majora and minora generally turning white. Mild swelling of the vulva may occur, while severe cases can lead to atrophy and adhesion of the clitoris, labia majora, and minora. Partial or complete disappearance of the labia minora, tightening of the posterior commissure, and narrowing of the vaginal opening with loss of elasticity may also occur, potentially affecting urination and sexual activity.

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