Nucleoside chemical synthesis

Author: Yao Qizheng
Publisher:
Publish Date: 2005-06-01
Features: This book provides over 500 reaction schemes along with corresponding analysis and discussion, as well as abundant references and literature. It covers fundamental theories, practical applications, and the latest research progress in nucleoside chemistry. The book is designed as both a textbook for foundational courses and a reference for researchers. It is a comprehensive and distinctive monograph on nucleoside chemical synthesis, divided into six chapters.
Chapter 1: Chemical Structure of Nucleosides and Nucleotides and Their Multifaceted Applications.
Chapter 2: The Significance of Chemical Synthesis of Nucleosides and Nucleotides.
Chapter 3: Focuses on the Synthesis Methods and Principles of Pyrimidine and Purine Nucleoside Bases, Briefly Introducing Other Types of Bases Used in Nucleoside Synthesis.
Chapter 4: Describes the Relationship Between Structural Variations of Nucleoside Sugars and Their Roles and Effects in Biomedicine, Systematically Introducing the Chemical Synthesis and Chemical Modification of Various Sugars, Including Methods, Principles, Effects of Reaction Conditions, and Related New Reagents.
Chapter 5: Chemical Synthesis of Nucleosides, Introducing Multiple Classical and New Methods for Establishing C—N and C—C Nucleoside Bonds, Discussing Their Mechanisms, Influencing Factors, and Stereochemistry in Nucleoside Synthesis.
Chapter 6: Various Chemical Reactions of Nucleosides, Emphasizing the Transfer of Sugars, Modification and Changes of Bases, and Modification and Changes of Sugars in Nucleosides, Leading to the Formation of New Nucleoside Synthesis Methods. It Also Discusses the Relationship Between These Nucleoside Structural Changes and Their Biological Effects.
At the end of the book, there is an appendix with relevant abbreviations and symbols. This book is suitable for senior undergraduate and graduate students, teachers, and researchers in fields such as organic chemistry, biochemistry, pharmacy, medicine, food science, and fine chemical engineering.
The book introduces the chemical structure of nucleosides and nucleotides and their multifaceted applications, the significance of chemical synthesis of nucleosides and nucleotides, the synthesis methods and principles of pyrimidine and purine nucleoside bases, and briefly covers other types of bases used in nucleoside synthesis.