Path Engineering: Third-generation Genetic Engineering

Author: Zhang Huizhan
Publisher:
Publish Date: 2002-01-01
Features: This book begins with an analysis of the logistics and energy flow of metabolic pathways within biological cells, revealing the unified principles of rigidity and flexibility in metabolic networks, as well as the coupling relationship between primary and secondary metabolism. Taking several typical enzyme molecular structures as examples, it examines the relative specificity of enzymes for substrates and the limitations of designing enzyme catalytic properties at the genetic level, abstracting general principles for metabolic pathway design. Finally, by describing several successful cases of metabolic pathway design and modification, it highlights the broad application prospects of pathway engineering.