Animal cell engineering

Author: Xu Yonghua
Publisher:
Publish Date: 2003-08-01
Features: "Modern Biotechnology Series" is a premium book series meticulously planned and launched by Chemical Industry Press. It has been listed as a key national book project under the "10th Five-Year Plan" by the National Press and Publication Administration. The series is edited by the renowned Chinese biotechnology expert, Mr. Jiao Ruishen, and written by authoritative scholars and experts from various relevant fields engaged in research, teaching, and industry. This book systematically and comprehensively introduces the fundamental principles, basic techniques, application achievements, and future development of animal cell engineering. After providing an overview of the development, content, and applications of animal cell engineering, it delves into the principles and basic techniques of cell culture and cell fusion, as well as the foundational advancements in animal cell engineering that utilize cell fusion to produce hybridomas and monoclonal antibodies. It emphasizes the techniques of animal cell gene expression systems and gene targeting, the use of chromosome vectors for gene transfer and the construction of artificial chromosomes, and their applications. Furthermore, based on the significant medical implications of stem cell biology, it introduces the research progress in embryonic stem cells and tissue stem cells. Finally, it explores the latest advancements in genetic manipulation of animal cells using these fundamental techniques, including the production of transgenic animals and embryos, as well as the progress in fish cell engineering and an overview of artificial cell research. Animal cell engineering has demonstrated increasingly significant contributions and roles in biopharmaceuticals and safeguarding human health. This book aims to provide readers with the fundamental theories, experimental techniques, and technical applications of animal cell engineering. Its rich content is suitable for researchers in the fields of cell engineering, genetic engineering, agricultural biotechnology, and medical biotechnology, as well as students and faculty from relevant disciplines at universities and colleges.