Gene targeting technology

Author: Yang Xiao
Publisher:
Publish Date: 2003-01-01
Features: The book includes common experimental methods and databases used in gene targeting research, serving as a reference for researchers, technicians, teachers, and graduate students in the fields of modern biology and medicine. Gene targeting is an experimental technique that directs genetic modifications in living organisms. Its development is built upon the achievements of embryonic stem cell technology and homologous recombination technology, and it has further advanced related technologies. Since the establishment of embryonic stem cell technology in the early 1980s and the birth of the first gene knockout mouse 15 years ago, research in gene targeting has progressed rapidly, bringing revolutionary changes to modern biology and medicine research and directly triggering many breakthroughs in various fields of modern biology and medicine, becoming one of the most direct and effective methods for studying gene functions in the post-genome era. The author has referred to a large number of recent domestic and international literature and combined practical experiences in recent years to provide a comprehensive introduction to the development of gene targeting technology and common research strategies, striving to reflect the latest research progress in this field.