What are the early symptoms of hand, foot, and mouth disease?

Patient's question:

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Doctor's answer:

Common hand, foot, and mouth disease is characterized by fever, scattered vesicles on the oral mucosa, maculopapular and vesicular lesions on the hands, feet, and buttocks, with inflammatory erythema around the vesicles and less fluid in the vesicles. In some cases, it may only present as rash or herpetic pharyngitis. The prognosis is good with no sequelae. Severe cases may involve neurological involvement and acute circulatory and respiratory failure, with a higher incidence in children under 3 years old.

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