Patient's question:
Patient: Female, age 25, weight 90 jin, in good physical condition, all pregnancy tests are normal. However, during the early Down syndrome screening at 13.3 weeks of pregnancy, the median multiple of free B-HCG was 7.816 (reference range: 0.0--2.50), and the 21-trisomy risk was 1:80 (reference range: <1:250). Both of these data are out of range, resulting in a high-risk result. Additionally, the male partner consumed soft drugs (ketamine) before conception. I would like to ask, is it certain that the baby will be a Down syndrome child? Is it possible that the baby cannot be kept? Is it because of the consumption of soft drugs that led to poor sperm quality, resulting in a Down syndrome child?Doctor's answer:
Analysis of the condition: Hello, the Down syndrome screening test measures the levels of alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG) in the mother's serum, combined with the pregnant woman's menstrual cycle, age, and gestational age at the time of blood collection, to calculate the risk factor for "Down syndrome children." This can detect 80% of Down syndrome cases. The results are not a definitive diagnosis but rather a risk factor, indicating the likelihood of having Down syndrome.Guidance: If the test results show a risk factor lower than 1/270, it means the risk is relatively low, and the chance of the fetus developing Down syndrome is less than 1%. However, if the risk factor is higher than 1/270, it indicates a higher risk of the fetus being affected, and further tests such as amniocentesis or chorionic villus sampling should be performed. Based on your situation, it is recommended to undergo either amniotic fluid or chorionic villus testing to clarify the condition. This is only a risk factor and cannot confirm a diagnosis. We hope this information is helpful to you.