Down syndrome screening Trisomy 21 1:400 is normal?

Patient's question:

Is a 1:400 result normal for the Down syndrome screening for trisomy 21? Are all pregnant women over 35 at high risk for trisomy 21?

Doctor's answer:

Analysis of the condition: Hello, your condition with this indication has relatively high risk. Suggestions: For this, it is recommended that you actively address it, preferably undergoing non-invasive DNA testing or amniocentesis for chromosomal abnormalities.

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