How much does a chromosome check cost?

Patient's question:

Azoospermia, infertility, unequal testicle size

Doctor's answer:

Analysis of the condition: Chromosome testing involves culturing peripheral blood in the presence of a cell growth stimulant—phytohemagglutinin (PHA) at 37°C for 72 hours to obtain a large number of dividing cells. Then, colchicine is added to arrest the dividing cells in metaphase for chromosome observation. The cells are then treated with hypotonic solution to expand them, reducing the entanglement and overlap between chromosomes. Finally, the cells are fixed on a slide using methanol and acetic acid for microscopic observation of chromosome structure and quantity.
The karyotype of a normal male consists of 44 autosomes and 2 sex chromosomes (X and Y), commonly represented as 46,XY in reports. A normal female has the same autosomes as males but 2 sex chromosomes (XX), typically represented as 46,XX. The number "46" indicates the total chromosome count; any number greater than or less than 46 is considered a chromosomal numerical abnormality. A missing sex chromosome is often denoted as "O."
Guidelines: Each human cell contains 23 pairs of chromosomes, including 22 pairs of autosomes and 1 pair of sex chromosomes. Sex chromosomes include the X and Y chromosomes. An embryo with a pair of X chromosomes develops into a female, while one with one X and one Y chromosome develops into a male. Thus, the normal sex chromosome composition for females is XX, and for males, it is XY. This means that all ova produced by female cells during meiosis contain one X chromosome. In males, half of the sperm contain an X chromosome, while the other half contain a Y chromosome.
Sperm and egg chromosomes carry genetic genes, recording the hereditary information passed from parents to offspring. Similarly, when there is an abnormality in sex chromosomes, it can lead to hereditary diseases. In male infertility, chromosomal abnormalities account for approximately 2% to 21% of cases, with oligozoospermia and azoospermia being particularly common.
Charges vary among different hospitals.