Patient's question:
I had two natural miscarriages, with the most recent one occurring at 19w+5. During the initial registration at Yinfeng Hospital, abnormal liver function was detected, and I was transferred to the Public Health Center for hospitalization. Unexpectedly, I started bleeding the day after admission, and after a week, on 4/26, I had another natural miscarriage. No D&C was performed post-miscarriage. On 5/25, I went to Yinfeng Hospital during the day for a chromosomal test, but suddenly experienced heavy bleeding that night, which lasted for five days. It was initially suspected to be menstruation. After the bleeding stopped, an ultrasound revealed retained tissue, leading to a D&C procedure.Doctor's answer:
Chromosomes are your genetic makeup, which remains unchanged throughout your life and generally does not change due to heavy bleeding or medication.inv(9) has little significant impact on you personally, but your chances of early miscarriage and embryonic arrest are higher than those of the general population. Generally, if the pregnancy is sustained beyond the fourth month, the risk of congenital defects in the fetus is similar to that of a normal pregnancy. The child may be completely normal or inherit your inv(9). Since each person's karyotype remains unchanged throughout their life, the risk of early miscarriage and embryonic arrest for you both persists. Although the karyotype is unchanging, improving lifestyle, maintaining a balanced diet, and avoiding toxic and harmful environments can still help enhance the quality of your sperm and eggs, indirectly reducing the risk of some early miscarriages and embryonic arrests. Of course, other tests related to embryonic arrest should also be conducted to rule out other causes.
Routine pre-pregnancy preparation: A woman's egg growth cycle is approximately 80 days, meaning the egg ovulated in the current month began growing two and a half months ago. A man's sperm production cycle is three months, so both partners should ideally start preparing three months before conception. You can begin by adjusting your lifestyle. For example, both partners should drink 2,000–3,000 ml of plain water daily to aid detoxification; ensure a sleep schedule of 10 p.m. to 3 a.m. daily, avoiding late nights as nighttime is the best time for rest and recovery; focus on consuming fresh vegetables and fruits to enhance antioxidant capacity; try to quit smoking and drinking alcohol, and avoid toxic and harmful environments. Women should take folic acid and vitamins appropriately three months before pregnancy and during the early pregnancy period. It is recommended for women to undergo a TORCH test before pregnancy and only conceive if the results are normal.