Patient's question:
Hello, I had a Down syndrome screening: HCG is greater than 2.5, mine is 3.4 plus, the doctor recommended I have an amniocentesis. What should I do? Thank you,Doctor's answer:
Analysis of the condition: Hello, the Down syndrome screening test measures the levels of alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG), free estriol (uE3), and open neural tube defects (OSD) in the mother's serum. By combining these results with the pregnant woman's menstrual cycle, age, and gestational age at the time of blood collection, a risk factor for "Down syndrome children" is calculated. This can detect 80% of Down syndrome cases. The results are not a definitive diagnosis but rather a risk factor, indicating the likelihood of having Down syndrome.Advice: The normal range for HCGb corrected MOM value is 0.5-2.5. However, MOM is a ratio, meaning the detected marker value in the pregnant woman's body divided by the median value of normal pregnant women at the same gestational age. If this single indicator fluctuates, there is no need to worry excessively, as it may also be due to inaccurate calculation of the pregnancy duration. It is unnecessary to let yourself panic. In your case, as long as other tests are normal, you can temporarily ignore this. Alternatively, you can undergo a four-dimensional ultrasound examination to clarify the situation. Currently, amniocentesis is not necessary. I hope this is helpful to you.