Patient's question:
Hello doctor, I have been married for two years without children. Last year, I was diagnosed with azoospermia and had a karyotype test, which showed 47, XXY. Is there any hope for IVF in this case? If IVF is successful, will the chromosomal abnormality be inherited? What is the survival rate of the fetus?Doctor's answer:
Hello, chromosomal diseases currently have no solutions or treatment methods in clinical practice. Even with successful assisted reproduction, the next generation would still be unhealthy, so IVF cannot be performed. The treatment for this condition at the current stage involves testosterone supplementation to promote masculinization, improve mental state, enhance sexual function, and thereby improve the patient's quality of life. The fertility issue for patients with this condition cannot be resolved, and only artificial insemination with donor sperm can be used. Wishing you a happy life!