Patient's question:
I am O negative blood type. I had a premature birth when I was pregnant with my first child, at 28 weeks, and unfortunately, the baby wasn't saved. Now I want to have a second child. What should I pay attention to?Doctor's answer:
Analysis of the condition: Hello, your situation is quite special. You have O-type blood and are also RH-negative. If the first pregnancy involves a non-O blood type, it may lead to neonatal hemolytic disease due to ABO blood type incompatibility in the newborn. However, if the first pregnancy involves an RH-positive blood type, your body will develop anti-RH antibodies. If the second pregnancy is with an RH-positive fetus, it may result in neonatal hemolytic disease due to RH blood type incompatibility.Recommendations: Since you are now pregnant with the second child, if the fetus is also RH-positive and non-O blood type, there is a possibility of both RH and ABO blood type incompatibility leading to neonatal hemolytic disease. Therefore, it is essential to check the titer of anti-A and anti-B blood. If the titer is high, timely treatment with antibody therapy is necessary. Additionally, the titer of anti-D should also be checked, as otherwise, there is a risk of neonatal hemolytic disease due to RH blood type incompatibility.